Spatial separation of two different pathways accounting for the generation of calcium signals in astrocytes

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Spatial separation of two different pathways accounting for the generation of calcium signals in astrocytes

Astrocytes integrate and process synaptic information and exhibit calcium (Ca2+) signals in response to incoming information from neighboring synapses. The generation of Ca2+ signals is mostly attributed to Ca2+ release from internal Ca2+ stores evoked by an elevated metabotropic glutamate receptor (mGluR) activity. Different experimental results associated the generation of Ca2+ signals to the...

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ژورنال

عنوان ژورنال: PLOS Computational Biology

سال: 2017

ISSN: 1553-7358

DOI: 10.1371/journal.pcbi.1005377